direkt zum Inhalt springen

direkt zum Hauptnavigationsmenü

Sie sind hier

TU Berlin

Inhalt des Dokuments


Search for publications

Journal Publications by GRK members

Oscillatory Correlates of Vibrotactile Frequency Processing in Human Working Memory
Citation key Spitzer2010
Author Spitzer, B., Wacker, E., and Blankenburg, F.
Pages 4496-502
Year 2010
DOI 10.1523/​JNEUROSCI.6041-09.2010
Journal J Neurosci.
Volume 30(12)
Month March
Abstract Previous animal research has revealed neuronal activity underlying short-term retention of vibrotactile stimuli, providing evidence for a parametric representation of stimulus frequency in primate tactile working memory (Romo et al., 1999). Here, we investigated the neural correlates of vibrotactile frequency processing in human working memory, using noninvasive electroencephalography (EEG). Participants judged the frequencies of vibrotactile stimuli delivered to the fingertip in a delayed match-to-sample frequency discrimination task. As expected, vibrotactile stimulation elicited pronounced steady-state evoked potentials, which were source-localized in primary somatosensory cortex. Furthermore, parametric analysis of induced EEG responses revealed that the frequency of stimulation was reflected by systematic modulations of synchronized oscillatory activity in nonprimary cortical areas. Stimulus processing was accompanied by frequency-dependent alpha-band responses (8–12 Hz) over dorsal occipital cortex. The critical new finding was that, throughout the retention interval, the stimulus frequency held in working memory was systematically represented by a modulation in prefrontal beta activity (20–25 Hz), which was source-localized to the inferior frontal gyrus. This modulation in oscillatory activity during stimulus retention was related to successful frequency discrimination, thus reflecting behaviorally relevant information. Together, the results complement previous findings of parametric working memory correlates in nonhuman primates and suggest that the quantitative representation of vibrotactile frequency in sensory memory entails systematic modulations of synchronized neural activity in human prefrontal cortex.
Link to publication Download Bibtex entry

To top

Zusatzinformationen / Extras

Quick Access:

Schnellnavigation zur Seite über Nummerneingabe

Auxiliary Functions