direkt zum Inhalt springen

direkt zum Hauptnavigationsmenü

Sie sind hier

TU Berlin

Inhalt des Dokuments

Search in All Publications

Search for publications

All Publications by GRK Members

Recruitment of oriens-lacunosum-moleculare interneurons during hippocampal ripples
Citation key Donoso2013
Author Pangalos, M., Donoso, J.R., Winterer, J., Zivkovic, A.R., Kempter, R., Maier, N., and Schmitz, D.
Pages 4398-4403
Year 2013
DOI 10.1073/pnas.1215496110
Journal Proc. Natl. Acad. Sci. USA
Volume 110
Abstract Sharp wave-associated  200 Hz ripple oscillations in the hippocampus have been implicated in the consolidation of memories. However, knowledge on mechanisms underlying ripples is still scarce, in particular with respect to synaptic involvement of specific cell types. Here we used cell-attached and whole-cell recordings in vitro to study activity of pyramidal cells and oriens-lacunosum-moleculare (O-LM) interneurons during ripples. O-LM cells received ripple-associated synaptic input that arrived delayed (3.3 ± 0.4 ms) with respect to the maximum amplitude of field ripples and was locked to the ascending phase of field oscillations (mean phase: 209 ± 6°). In line, O-LM cells episodically discharged late during ripples ( 6.5 ms after the ripple maximum), and firing was phase locked to field oscillations (mean phase: 219 ± 9°). Our data unveil recruitment of O-LM neurons during ripples, suggesting a new role of this cell type during sharp wave-associated activity.
Link to original publication Download Bibtex entry

To top

Import Publication

Upload BibTeX

Export all entries to BibTex

Zusatzinformationen / Extras

Quick Access:

Schnellnavigation zur Seite über Nummerneingabe

Auxiliary Functions